THERAPEUTIC POTENTIAL OF MITOCHONDRIAL UNCOUPLERS FOR THE TREATMENT OF METABOLIC ASSOCIATED FATTY LIVER DISEASE AND NASH

Background: Mitochondrial uncouplers shuttle protons across the inner mitochondrial membrane via a pathway that is independent of adenosine triphosphate (ATP) synthase, thereby uncoupling nutrient oxidation from ATP production and dissipating the proton gradient as heat.While initial toxicity concerns hindered their therapeutic development in the e

An otherwise healthy young adult female presented to our clinic with a second episode of varicella.Our patient had a ANTI-STRESS diffuse vesicular rash, reminiscent of childhood varicella, accompanied by constitutional symptoms.This rare presentation of a common virus required careful diagnostic and therapeutic decision-making, with a targeted appr